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Pharmacophore and docking-based sequential virtual screening for the identification of novel Sigma 1 receptor ligands
Sigma 1 receptor (σ1), a small transmembrane protein expressed in most human cells participates in modulating the function of other membrane proteins such as G protein coupled receptors and ion channels. Several ligands targeting this receptor are currently in clinical trials for the treatment of Al...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Biomedical Informatics
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822515/ https://www.ncbi.nlm.nih.gov/pubmed/31719769 http://dx.doi.org/10.6026/97320630015586 |