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Pharmacophore and docking-based sequential virtual screening for the identification of novel Sigma 1 receptor ligands

Sigma 1 receptor (σ1), a small transmembrane protein expressed in most human cells participates in modulating the function of other membrane proteins such as G protein coupled receptors and ion channels. Several ligands targeting this receptor are currently in clinical trials for the treatment of Al...

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Detalles Bibliográficos
Autores principales:	Alamri, Mubarak A, Alamri, Mohammed A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Biomedical Informatics 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822515/ https://www.ncbi.nlm.nih.gov/pubmed/31719769 http://dx.doi.org/10.6026/97320630015586

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