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Effect and Mechanism of the Bruton Tyrosine Kinase (Btk) Inhibitor Ibrutinib on Rat Model of Diabetic Foot Ulcers

BACKGROUND: Diabetes causes damage to the soft tissue and bone structure of the foot, referred to as “diabetic foot”. Ibrutinib is a Bruton tyrosine kinase (Btk) inhibitor, and the role and mechanism of ibrutinib on the diabetic foot have not been elucidated. MATERIAL/METHODS: Male Wister rats were...

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Detalles Bibliográficos
Autores principales: Yang, Xuedong, Cao, Zhenhao, Wu, Peigang, Li, Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822560/
https://www.ncbi.nlm.nih.gov/pubmed/31644524
http://dx.doi.org/10.12659/MSM.916950