miRNA-103 promotes chondrocyte apoptosis by down-regulation of Sphingosine kinase-1 and ameliorates PI3K/AKT pathway in osteoarthritis

Objectives: The aim of the present study was to determine the effects of miRNA-103 on chondrocyte apoptosis and molecular mechanisms in osteoarthritis (OA) progression. Methods: The cell proliferation, apoptosis, and recovery ability were measured by cell counting kit-8 (CCK-8), flow cytometry, and...

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Detalles Bibliográficos
Autores principales: Li, Fang, Yao, Jianhua, Hao, Qingqing, Duan, Zheping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822578/
https://www.ncbi.nlm.nih.gov/pubmed/31652455
http://dx.doi.org/10.1042/BSR20191255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822578/
https://www.ncbi.nlm.nih.gov/pubmed/31652455
http://dx.doi.org/10.1042/BSR20191255

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