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A novel benzoxazinone derivative YLT-LL-11 inhibits diffuse large B-cell lymphoma growth via inducing cell cycle arrest and apoptosis

Diffuse large B-cell lymphoma (DLBCL) is a clinically aggressive B-cell non-Hodgkin’s lymphoma (NHL) with high treatment difficulty and high relapse rate. The bromodomain and extra-terminal (BET) proteins play significant roles in supporting the transcription of known DLBCL oncogene MYC, which provi...

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Detalles Bibliográficos
Autores principales: Peng, Cuiting, Sun, Changzhen, Wang, Ningyu, He, Yuanmin, Xu, Jixiang, Deng, Yongqiong, Gao, Lanyang, Zhong, Jianqiao, Xiong, Xia, Liu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822579/
https://www.ncbi.nlm.nih.gov/pubmed/31527063
http://dx.doi.org/10.1042/BSR20190828