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A novel benzoxazinone derivative YLT-LL-11 inhibits diffuse large B-cell lymphoma growth via inducing cell cycle arrest and apoptosis
Diffuse large B-cell lymphoma (DLBCL) is a clinically aggressive B-cell non-Hodgkin’s lymphoma (NHL) with high treatment difficulty and high relapse rate. The bromodomain and extra-terminal (BET) proteins play significant roles in supporting the transcription of known DLBCL oncogene MYC, which provi...
Autores principales: | Peng, Cuiting, Sun, Changzhen, Wang, Ningyu, He, Yuanmin, Xu, Jixiang, Deng, Yongqiong, Gao, Lanyang, Zhong, Jianqiao, Xiong, Xia, Liu, Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822579/ https://www.ncbi.nlm.nih.gov/pubmed/31527063 http://dx.doi.org/10.1042/BSR20190828 |
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