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Resolution of angstrom-scale protein-conformational changes by analyzing fluorescence anisotropy
Conformational changes within typical protein molecules are rapid and small, making their quantitative resolution challenging. These changes generally involve rotational motions, and may thus be resolved by determining changes in the orientation of a fluorescent label that assumes a unique orientati...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822697/ https://www.ncbi.nlm.nih.gov/pubmed/31488909 http://dx.doi.org/10.1038/s41594-019-0274-2 |