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Modelling Forced Vital Capacity in Idiopathic Pulmonary Fibrosis: Optimising Trial Design

INTRODUCTION: Forced vital capacity is the only registrational endpoint in idiopathic pulmonary fibrosis clinical trials. As most new treatments will be administered on top of standard of care, estimating treatment response will become more challenging. We developed a simulation model to quantify va...

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Detalles Bibliográficos
Autores principales: Santermans, Eva, Ford, Paul, Kreuter, Michael, Verbruggen, Nadia, Meyvisch, Paul, Wuyts, Wim A., Brown, Kevin K., Lederer, David J., Byrne, Adam J., Molyneaux, Philip L., Sivananthan, Arunon, Moor, Catharina C., Maher, Toby M., Wijsenbeek, Marlies
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822798/
https://www.ncbi.nlm.nih.gov/pubmed/31565781
http://dx.doi.org/10.1007/s12325-019-01093-3