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Pharmacokinetics and Bioequivalence of Memantine Tablet and a New Dry Syrup Formulation in Healthy Japanese Males: Two Single-Dose Crossover Studies

INTRODUCTION: Memantine hydrochloride, an N-methyl-D-aspartate receptor antagonist, is used to treat Alzheimer’s disease (AD). A new dry syrup formulation containing memantine hydrochloride has been developed to improve medication adherence in AD patients and to reduce family and caregiver burden. T...

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Detalles Bibliográficos
Autores principales: Maekawa, Yutaro, Hasegawa, Setsuo, Ishizuka, Tomoko, Shiosakai, Kazuhito, Ishizuka, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822834/
https://www.ncbi.nlm.nih.gov/pubmed/31399883
http://dx.doi.org/10.1007/s12325-019-01044-y