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The coupling of the M2 muscarinic receptor to its G protein is voltage dependent

G protein coupled receptors (GPCRs) participate in the majority of signal transduction processes in the body. Specifically, the binding of an external agonist promotes coupling of the GPCR to its G protein and this, in turn, induces downstream signaling. Recently, it was shown that agonist binding t...

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Detalles Bibliográficos
Autores principales: Ben-Chaim, Yair, Broide, Chava, Parnas, Hanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822938/
https://www.ncbi.nlm.nih.gov/pubmed/31671117
http://dx.doi.org/10.1371/journal.pone.0224367