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Native adiponectin in serum binds to mammalian cells expressing T-cadherin, but not AdipoRs or calreticulin

Adiponectin is an adipocyte-derived atypically abundant circulating factor that protects various organs and tissues through its receptors, AdipoRs, calreticulin, and T-cadherin. To identify the major binding partner of circulating native adiponectin, we expressed these receptors on the surface of HE...

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Detalles Bibliográficos
Autores principales: Kita, Shunbun, Fukuda, Shiro, Maeda, Norikazu, Shimomura, Iichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822988/
https://www.ncbi.nlm.nih.gov/pubmed/31647413
http://dx.doi.org/10.7554/eLife.48675