AFF1 acetylation by p300 temporally inhibits transcription during genotoxic stress response

Soon after exposure to genotoxic reagents, mammalian cells inhibit transcription to prevent collisions with repair machinery and to mount a proper DNA damage response. However, mechanisms underlying early transcriptional inhibition are poorly understood. In this report, we show that site-specific ac...

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Detalles Bibliográficos
Autores principales: Kumari, Nidhi, Hassan, M. Abul, Lu, Xiangdong, Roeder, Robert G., Biswas, Debabrata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823056/
https://www.ncbi.nlm.nih.gov/pubmed/31611376
http://dx.doi.org/10.1073/pnas.1907097116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823056/
https://www.ncbi.nlm.nih.gov/pubmed/31611376
http://dx.doi.org/10.1073/pnas.1907097116

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