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AFF1 acetylation by p300 temporally inhibits transcription during genotoxic stress response
Soon after exposure to genotoxic reagents, mammalian cells inhibit transcription to prevent collisions with repair machinery and to mount a proper DNA damage response. However, mechanisms underlying early transcriptional inhibition are poorly understood. In this report, we show that site-specific ac...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823056/ https://www.ncbi.nlm.nih.gov/pubmed/31611376 http://dx.doi.org/10.1073/pnas.1907097116 |