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SHP-2 in Lymphocytes' Cytokine and Inhibitory Receptor Signaling

Somewhat counterintuitively, the tyrosine phosphatase SHP-2 (SH2 domain-containing protein tyrosine phosphatase-2) is crucial for the activation of extracellular signal-regulated kinase (ERK) downstream of various growth factor receptors, thereby exerting essential developmental functions. This phos...

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Detalles Bibliográficos
Autores principales: Niogret, Charlène, Birchmeier, Walter, Guarda, Greta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823243/
https://www.ncbi.nlm.nih.gov/pubmed/31708921
http://dx.doi.org/10.3389/fimmu.2019.02468