Cargando…
SHP-2 in Lymphocytes' Cytokine and Inhibitory Receptor Signaling
Somewhat counterintuitively, the tyrosine phosphatase SHP-2 (SH2 domain-containing protein tyrosine phosphatase-2) is crucial for the activation of extracellular signal-regulated kinase (ERK) downstream of various growth factor receptors, thereby exerting essential developmental functions. This phos...
Autores principales: | Niogret, Charlène, Birchmeier, Walter, Guarda, Greta |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823243/ https://www.ncbi.nlm.nih.gov/pubmed/31708921 http://dx.doi.org/10.3389/fimmu.2019.02468 |
Ejemplares similares
-
Shp-2 is critical for ERK and metabolic engagement downstream of IL-15 receptor in NK cells
por: Niogret, Charlène, et al.
Publicado: (2019) -
Editorial: Inhibitory Receptors and Pathways of Lymphocytes
por: Carmo, Alexandre M., et al.
Publicado: (2020) -
Negative Regulation of Ros Receptor Tyrosine Kinase Signaling: An Epithelial Function of the Sh2 Domain Protein Tyrosine Phosphatase Shp-1
por: Keilhack, Heike, et al.
Publicado: (2001) -
Exploration of T cell immune responses by expression of a dominant-negative SHP1 and SHP2
por: Taylor, Julia, et al.
Publicado: (2023) -
The neurite outgrowth multiadaptor RhoGAP, NOMA-GAP, regulates neurite extension through SHP2 and Cdc42
por: Rosário, Marta, et al.
Publicado: (2007)