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A treatment approach for couples with disrupted sperm DNA integrity and recurrent ART failure

OBJECTIVE: To test a novel method to select spermatozoa with high chromatin integrity. DESIGN: Specimens with high sperm chromatin fragmentation (SCF) were selected by density gradient selection (DGS) and microfluidic sperm sorting (MSS). SETTING: Academic medical center. PATIENT(S): Ejaculates from...

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Detalles Bibliográficos
Autores principales: Parrella, Alessandra, Keating, Derek, Cheung, Stephanie, Xie, Philip, Stewart, Joshua D., Rosenwaks, Zev, Palermo, Gianpiero D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823295/
https://www.ncbi.nlm.nih.gov/pubmed/31418108
http://dx.doi.org/10.1007/s10815-019-01543-5