Combination of ERK2 inhibitor VX-11e and voreloxin synergistically enhances anti-proliferative and pro-apoptotic effects in leukemia cells

ERK1/2 inhibitors are new promising anticancer drugs. The aim of this study was to investigate the effect of the combination of ERK2 inhibitor VX-11e and voreloxin on MOLM-14, K562, REH and MOLT-4 leukemia cell lines. We found that VX-11e alone and in combination with voreloxin significantly decreas...

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Detalles Bibliográficos
Autores principales: Jasek-Gajda, Ewa, Jurkowska, Halina, Jasińska, Małgorzata, Litwin, Jan A., Lis, Grzegorz J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823322/
https://www.ncbi.nlm.nih.gov/pubmed/31482470
http://dx.doi.org/10.1007/s10495-019-01564-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823322/
https://www.ncbi.nlm.nih.gov/pubmed/31482470
http://dx.doi.org/10.1007/s10495-019-01564-6

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