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(18)F-FIMP: a LAT1-specific PET probe for discrimination between tumor tissue and inflammation

Positron emission tomography (PET) imaging can assist in the early-phase diagnostic and therapeutic evaluation of tumors. Here, we report the radiosynthesis, small animal PET imaging, and biological evaluation of a L-type amino acid transporter 1 (LAT1)-specific PET probe, (18)F-FIMP. This probe dem...

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Detalles Bibliográficos
Autores principales: Nozaki, Satoshi, Nakatani, Yuka, Mawatari, Aya, Shibata, Nina, Hume, William E., Hayashinaka, Emi, Wada, Yasuhiro, Doi, Hisashi, Watanabe, Yasuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823354/
https://www.ncbi.nlm.nih.gov/pubmed/31673030
http://dx.doi.org/10.1038/s41598-019-52270-x