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Targeting ERβ in Macrophage Reduces Crown-like Structures in Adipose Tissue by Inhibiting Osteopontin and HIF-1α

Proinflammatory processes in adipose tissue contribute to development of breast cancer and insulin resistance. Crown-like structures (CLS) are histologic hallmarks of the proinflammatory process in adipose tissue. CLS are microscopic foci of dying adipocytes surrounded by macrophages mostly derived...

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Detalles Bibliográficos
Autores principales: Wang, Li, Zhao, Rui-peng, Song, Xiao-yu, Wu, Wan-fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823357/
https://www.ncbi.nlm.nih.gov/pubmed/31673032
http://dx.doi.org/10.1038/s41598-019-52265-8