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Single cell analysis to dissect molecular heterogeneity and disease evolution in metastatic melanoma

Originally described as interpatient variability, tumour heterogeneity has now been demonstrated to occur intrapatiently, within the same lesion, or in different lesions of the same patient. Tumour heterogeneity involves both genetic and epigenetic changes. Intrapatient heterogeneity is responsible...

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Detalles Bibliográficos
Autores principales: Fattore, Luigi, Ruggiero, Ciro Francesco, Liguoro, Domenico, Mancini, Rita, Ciliberto, Gennaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823362/
https://www.ncbi.nlm.nih.gov/pubmed/31672982
http://dx.doi.org/10.1038/s41419-019-2048-5