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Single cell analysis to dissect molecular heterogeneity and disease evolution in metastatic melanoma
Originally described as interpatient variability, tumour heterogeneity has now been demonstrated to occur intrapatiently, within the same lesion, or in different lesions of the same patient. Tumour heterogeneity involves both genetic and epigenetic changes. Intrapatient heterogeneity is responsible...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823362/ https://www.ncbi.nlm.nih.gov/pubmed/31672982 http://dx.doi.org/10.1038/s41419-019-2048-5 |