Salt-inducible kinase 1 regulates bone anabolism via the CRTC1–CREB–Id1 axis

New bone anabolic agents for the effective treatment of bone metabolic diseases like osteoporosis are of high clinical demand. In the present study, we reveal the function of salt-inducible kinase 1 (SIK1) in regulating osteoblast differentiation. Gene knockdown of SIK1 but not of SIK2 or SIK3 expre...

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Detalles Bibliográficos
Autores principales: Kim, Min Kyung, Kwon, Jun-Oh, Song, Min-Kyoung, Kim, Bongjun, Kim, Haemin, Lee, Zang Hee, Koo, Seung-Hoi, Kim, Hong-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823377/
https://www.ncbi.nlm.nih.gov/pubmed/31672960
http://dx.doi.org/10.1038/s41419-019-1915-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823377/
https://www.ncbi.nlm.nih.gov/pubmed/31672960
http://dx.doi.org/10.1038/s41419-019-1915-4

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