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Split selectable markers

Selectable markers are widely used in transgenesis and genome editing for selecting engineered cells with a desired genotype but the variety of markers is limited. Here we present split selectable markers that each allow for selection of multiple “unlinked” transgenes in the context of lentivirus-me...

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Detalles Bibliográficos
Autores principales: Jillette, Nathaniel, Du, Menghan, Zhu, Jacqueline Jufen, Cardoz, Peter, Cheng, Albert Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823381/
https://www.ncbi.nlm.nih.gov/pubmed/31672965
http://dx.doi.org/10.1038/s41467-019-12891-2