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Oct4-mediated reprogramming induces embryonic-like microRNA expression signatures in human fibroblasts

Oct4-mediated reprogramming has recently become a novel tool for the generation of various cell types from differentiated somatic cells. Although molecular mechanisms underlying this process are unknown, it is well documented that cells over-expressing Oct4 undergo transition from differentiated sta...

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Detalles Bibliográficos
Autores principales: Peskova, Lucie, Cerna, Katerina, Oppelt, Jan, Mraz, Marek, Barta, Tomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823439/
https://www.ncbi.nlm.nih.gov/pubmed/31673026
http://dx.doi.org/10.1038/s41598-019-52294-3