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Oct4-mediated reprogramming induces embryonic-like microRNA expression signatures in human fibroblasts
Oct4-mediated reprogramming has recently become a novel tool for the generation of various cell types from differentiated somatic cells. Although molecular mechanisms underlying this process are unknown, it is well documented that cells over-expressing Oct4 undergo transition from differentiated sta...
Autores principales: | Peskova, Lucie, Cerna, Katerina, Oppelt, Jan, Mraz, Marek, Barta, Tomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823439/ https://www.ncbi.nlm.nih.gov/pubmed/31673026 http://dx.doi.org/10.1038/s41598-019-52294-3 |
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