Comprehensive analysis of POLE and POLD1 Gene Variations identifies cancer patients potentially benefit from immunotherapy in Chinese population

POLE/POLD1 gene variants have been suggested as potential markers for immunotherapy due to their significant association with the tumor mutational burden (TMB), an effective indicator for response prediction in immunotherapy. However, the correlation of POLE/POLD1 variants with MSI, MMR, TMB, MMR-re...

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Detalles Bibliográficos
Autores principales: Yao, Jianfei, Gong, Yuan, Zhao, Wei, Han, Zhifeng, Guo, Shaohua, Liu, Hongyi, Peng, Xiumei, Xiao, Wenhua, Li, Yuemin, Dang, Shiying, Liu, Guifeng, Li, Lifeng, Huang, Tanxiao, Chen, Shifu, Song, Lele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823448/
https://www.ncbi.nlm.nih.gov/pubmed/31673068
http://dx.doi.org/10.1038/s41598-019-52414-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823448/
https://www.ncbi.nlm.nih.gov/pubmed/31673068
http://dx.doi.org/10.1038/s41598-019-52414-z

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