Mitochondria damaged by Oxygen Glucose Deprivation can be Restored through Activation of the PI3K/Akt Pathway and Inhibition of Calcium Influx by Amlodipine Camsylate

Amlodipine, a L-type calcium channel blocker, has been reported to have a neuroprotective effect in brain ischemia. Mitochondrial calcium overload leads to apoptosis of cells in neurologic diseases. We evaluated the neuroprotective effects of amlodipine camsylate (AC) on neural stem cells (NSCs) inj...

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Detalles Bibliográficos
Autores principales: Park, Hyun-Hee, Han, Myung-Hoon, Choi, Hojin, Lee, Young Joo, Kim, Jae Min, Cheong, Jin Hwan, Ryu, Je Il, Lee, Kyu-Yong, Koh, Seong-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823474/
https://www.ncbi.nlm.nih.gov/pubmed/31673096
http://dx.doi.org/10.1038/s41598-019-52083-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823474/
https://www.ncbi.nlm.nih.gov/pubmed/31673096
http://dx.doi.org/10.1038/s41598-019-52083-y

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