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A multi-modal data resource for investigating topographic heterogeneity in patient-derived xenograft tumors

Patient-derived xenografts (PDXs) are an essential pre-clinical resource for investigating tumor biology. However, cellular heterogeneity within and across PDX tumors can strongly impact the interpretation of PDX studies. Here, we generated a multi-modal, large-scale dataset to investigate PDX heter...

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Detalles Bibliográficos
Autores principales: Rajaram, Satwik, Roth, Maike A., Malato, Julia, VandenBerg, Scott, Hann, Byron, Atreya, Chloe E., Altschuler, Steven J., Wu, Lani F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823477/
https://www.ncbi.nlm.nih.gov/pubmed/31672976
http://dx.doi.org/10.1038/s41597-019-0225-0