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A multi-modal data resource for investigating topographic heterogeneity in patient-derived xenograft tumors
Patient-derived xenografts (PDXs) are an essential pre-clinical resource for investigating tumor biology. However, cellular heterogeneity within and across PDX tumors can strongly impact the interpretation of PDX studies. Here, we generated a multi-modal, large-scale dataset to investigate PDX heter...
Autores principales: | Rajaram, Satwik, Roth, Maike A., Malato, Julia, VandenBerg, Scott, Hann, Byron, Atreya, Chloe E., Altschuler, Steven J., Wu, Lani F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823477/ https://www.ncbi.nlm.nih.gov/pubmed/31672976 http://dx.doi.org/10.1038/s41597-019-0225-0 |
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