Alleviation of murine osteoarthritis by deletion of the focal adhesion mechanosensitive adapter, Hic-5

Excessive mechanical stress is a major cause of knee osteoarthritis. However, the mechanism by which the mechanical stress begets osteoarthritis development remains elusive. Hydrogen peroxide-inducible clone-5 (Hic-5; TGFβ1i1), a TGF-β inducible focal adhesion adaptor, has previously been reported a...

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Detalles Bibliográficos
Autores principales: Miyauchi, Aya, Kim-Kaneyama, Joo-ri, Lei, Xiao-Feng, Chang, Song Ho, Saito, Taku, Haraguchi, Shogo, Miyazaki, Takuro, Miyazaki, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823501/
https://www.ncbi.nlm.nih.gov/pubmed/31673109
http://dx.doi.org/10.1038/s41598-019-52301-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823501/
https://www.ncbi.nlm.nih.gov/pubmed/31673109
http://dx.doi.org/10.1038/s41598-019-52301-7

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