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Methylphenidate Dose-Dependently Affects Aggression and Improves Fear Extinction and Anxiety in BALB/cJ Mice

Overt aggression, increased anxiety, and dysfunctional fear processing are often observed in individuals with conduct disorder (CD) and attention-deficit hyperactivity disorder (ADHD). Methylphenidate (MPH), a psychostimulant increasing dopamine and noradrenaline tone, is effective in reducing aggre...

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Detalles Bibliográficos
Autores principales: Jager, Amanda, Kanters, Doranda, Geers, Femke, Buitelaar, Jan K., Kozicz, Tamas, Glennon, Jeffrey C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823535/
https://www.ncbi.nlm.nih.gov/pubmed/31708820
http://dx.doi.org/10.3389/fpsyt.2019.00768