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GLP-1 receptor agonist liraglutide has a neuroprotective effect on an aged rat model of Wolfram syndrome

Wolfram syndrome (WS) is a rare neurodegenerative disorder that is mainly characterized by diabetes mellitus, optic nerve atrophy, deafness, and progressive brainstem degeneration. Treatment with GLP-1 receptor agonists has shown a promising anti-diabetic effect in WS treatment in both animal models...

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Detalles Bibliográficos
Autores principales:	Seppa, Kadri, Toots, Maarja, Reimets, Riin, Jagomäe, Toomas, Koppel, Tuuliki, Pallase, Maia, Hasselholt, Stine, Krogsbæk Mikkelsen, Maiken, Randel Nyengaard, Jens, Vasar, Eero, Terasmaa, Anton, Plaas, Mario
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823542/ https://www.ncbi.nlm.nih.gov/pubmed/31673100 http://dx.doi.org/10.1038/s41598-019-52295-2

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