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Thymidine Phosphorylase Expression and Microvascular Density Correlation Analysis in Canine Mammary Tumor: Possible Prognostic Factor in Breast Cancer

Purpose: The thymidine phosphorylase (TP) is a key enzyme involved in the metabolism of pyrimidines. Inhibition or downregulation of this enzyme causes accumulation of metabolites with consequences in DNA replication. TP regulates angiogenesis and chemotactic activity of endothelial cells. Different...

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Detalles Bibliográficos
Autores principales: Zizzo, Nicola, Passantino, Giuseppe, D'alessio, Roberta Maria, Tinelli, Antonella, Lopresti, Giuseppe, Patruno, Rosa, Tricarico, Domenico, Maqoud, Fatima, Scala, Rosa, Zito, Francesco Alfredo, Ranieri, Girolamo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823610/
https://www.ncbi.nlm.nih.gov/pubmed/31709268
http://dx.doi.org/10.3389/fvets.2019.00368