Cargando…

Thymidine Phosphorylase Expression and Microvascular Density Correlation Analysis in Canine Mammary Tumor: Possible Prognostic Factor in Breast Cancer

Purpose: The thymidine phosphorylase (TP) is a key enzyme involved in the metabolism of pyrimidines. Inhibition or downregulation of this enzyme causes accumulation of metabolites with consequences in DNA replication. TP regulates angiogenesis and chemotactic activity of endothelial cells. Different...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zizzo, Nicola, Passantino, Giuseppe, D'alessio, Roberta Maria, Tinelli, Antonella, Lopresti, Giuseppe, Patruno, Rosa, Tricarico, Domenico, Maqoud, Fatima, Scala, Rosa, Zito, Francesco Alfredo, Ranieri, Girolamo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Veterinary Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823610/ https://www.ncbi.nlm.nih.gov/pubmed/31709268 http://dx.doi.org/10.3389/fvets.2019.00368

Ejemplares similares

Immunohistochemical, pharmacovigilance, and omics analyses reveal the involvement of ATP-sensitive K(+) channel subunits in cancers: role in drug–disease interactions
por: Maqoud, Fatima, et al.
Publicado: (2023)

Microvascular Density, Endothelial Area, and Ki-67 Proliferative Index Correlate Each Other in Cat Post-Injection Fibrosarcoma
por: Patruno, Rosa, et al.
Publicado: (2020)

Cell Cycle Regulation by Ca(2+)-Activated K(+) (BK) Channels Modulators in SH-SY5Y Neuroblastoma Cells
por: Maqoud, Fatima, et al.
Publicado: (2018)

A possible role of thymidine phosphorylase expression and5-fluorouracil increased sensitivity in oropharyngeal cancer patients
por: Ranieri, G, et al.
Publicado: (2007)

The hydroxypropyl‐β‐cyclodextrin‐minoxidil inclusion complex improves the cardiovascular and proliferative adverse effects of minoxidil in male rats: Implications in the treatment of alopecia
por: Maqoud, Fatima, et al.
Publicado: (2020)

Consequences of SUR2[A478V] Mutation in Skeletal Muscle of Murine Model of Cantu Syndrome
por: Scala, Rosa, et al.
Publicado: (2021)

Pathophysiological Consequences of KATP Channel Overactivity and Pharmacological Response to Glibenclamide in Skeletal Muscle of a Murine Model of Cantù Syndrome
por: Scala, Rosa, et al.
Publicado: (2020)

VEGF concentration from plasma-activated platelets rich correlates with microvascular density and grading in canine mast cell tumour spontaneous model
por: Patruno, R, et al.
Publicado: (2009)

The cytosol activity of thymidine phosphorylase in endometrial cancer
por: Miszczak-Zaborska, Elżbieta, et al.
Publicado: (2008)

Expression of Thymidine Phosphorylase in Human Gastric Carcinoma
por: Takebayashi, Yuji, et al.
Publicado: (1996)

Expression of the thymidine phosphorylase gene in epithelial ovarian cancer
por: Hata, K, et al.
Publicado: (1999)

Vorinostat synergises with capecitabine through upregulation of thymidine phosphorylase
por: Di Gennaro, E, et al.
Publicado: (2010)

A monoclonal antibody-based sandwich ELISA for measuring canine Thymidine kinase 1 protein and its role as biomarker in canine lymphoma
por: Sharif, Hanan, et al.
Publicado: (2023)

Impact of thymidine phosphorylase surexpression on fluoropyrimidine activity and on tumour angiogenesis
por: Marchetti, S, et al.
Publicado: (2001)

Modulation of thymidine phosphorylase by neoadjuvant chemotherapy in primary breast cancer
por: Toi, M, et al.
Publicado: (2004)

Structures of native human thymidine phosphorylase and in complex with 5-iodouracil
por: Mitsiki, Eirini, et al.
Publicado: (2009)

Thymidine Phosphorylase Gene Expression in Stage III Colorectal Cancer
por: Lindskog, Elinor B., et al.
Publicado: (2012)

Depletion of plasma thymidine results in growth retardation and mitochondrial myopathy in mice overexpressing human thymidine phosphorylase
por: Harada, Naomoto, et al.
Publicado: (2023)

Tryptase mast cell density, protease-activated receptor-2 microvascular density, and classical microvascular density evaluation in gastric cancer patients undergoing surgery: possible translational relevance
por: Ammendola, Michele, et al.
Publicado: (2017)

Tumour‐associated macrophages correlate with microvascular bed extension in colorectal cancer patients
por: Marech, Ilaria, et al.
Publicado: (2016)

The Expression of Thymidine Phosphorylase in Cancer-infiltrating Inflammatory Cells in Stomach Cancer
por: Jang, Joung Soon, et al.
Publicado: (2007)

Research development of the relationship between thymidine phosphorylase expression and colorectal carcinoma
por: Ye, Dian-Jun, et al.
Publicado: (2013)

Biochemical abnormalities in a patient with thymidine phosphorylase deficiency with fatal outcome
por: Bakker, Jaap A., et al.
Publicado: (2010)

Liver as a Source for Thymidine Phosphorylase Replacement in Mitochondrial Neurogastrointestinal Encephalomyopathy
por: Boschetti, Elisa, et al.
Publicado: (2014)

Possible role of thymidine phosphorylase in gynecological tumors as an individualized treatment strategy
por: Shida, Masako, et al.
Publicado: (2016)

Safety and Efficacy of Erythrocyte Encapsulated Thymidine Phosphorylase in Mitochondrial Neurogastrointestinal Encephalomyopathy
por: Levene, Michelle, et al.
Publicado: (2019)

Thymidine Phosphorylase Is Increased in COVID-19 Patients in an Acuity-Dependent Manner
por: Li, Wei, et al.
Publicado: (2021)

Inflammatory Related Reactions in Humans and in Canine Breast Cancers, A Spontaneous Animal Model of Disease
por: Tricarico, Domenico, et al.
Publicado: (2022)

Mast Cells Density Positive to Tryptase Correlate with Microvascular Density in both Primary Gastric Cancer Tissue and Loco-Regional Lymph Node Metastases from Patients That Have Undergone Radical Surgery
por: Ammendola, Michele, et al.
Publicado: (2016)

Expression of Thymidine Phosphorylase in Lymph Nodes Involved with Mycosis Fungoides and Sézary Syndrome
por: Nie, Xingcao, et al.
Publicado: (2011)

Comparison of thymidine phosphorylase expression and prognostic factors in gallbladder and bile duct cancer
por: Won, Hye Sung, et al.
Publicado: (2010)

Thymidine phosphorylase expression is associated with time to progression in patients with metastatic colorectal cancer
por: Lindskog, Elinor Bexe, et al.
Publicado: (2014)

4-Methylumbelliferone inhibits ovarian cancer growth by suppressing thymidine phosphorylase expression
por: Tamura, Ryosuke, et al.
Publicado: (2014)

Correction: Liver as a Source for Thymidine Phosphorylase Replacement in Mitochondrial Neurogastrointestinal Encephalomyopathy
Publicado: (2014)

Erratum to research development of the relationship between thymidine phosphorylase expression and colorectal carcinoma
por: Ye, Dian-Jun, et al.
Publicado: (2013)

Distinct substrate specificity and physicochemical characterization of native human hepatic thymidine phosphorylase
por: Oh, Taesung, et al.
Publicado: (2018)

Expression of Thymidine Phosphorylase in Primary Human Renal Cell Carcinoma by ELISA Method
por: Kinsui, Hidetoshi, et al.
Publicado: (2002)

Synthesis of Thymidine Phosphorylase Inhibitor Based on Quinoxaline Derivatives and Their Molecular Docking Study
por: Almandil, Noor Barak, et al.
Publicado: (2019)

Expression and Retention of Thymidine Phosphorylase in Cultured Reticulocytes as a Novel Treatment for MNGIE
por: Meinders, Marjolein, et al.
Publicado: (2020)

Mesenchymal stem cells anchored with thymidine phosphorylase for doxifluridine-mediated cancer therapy
por: Tarar, Ammar, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_62gtoj78jd8p5b3v74gjhrdugu