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Aquaporin-1 attenuates macrophage-mediated inflammatory responses by inhibiting p38 mitogen-activated protein kinase activation in lipopolysaccharide-induced acute kidney injury

OBJECTIVE: This study was designed to investigate the role of AQP1 in the development of LPS-induced AKI and its potential regulatory mechanisms in the inflammatory responses of macrophages. METHODS: Male Wistar rats were injected intraperitoneally with LPS, and biochemical and histological renal da...

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Detalles Bibliográficos
Autores principales: Li, Bohui, Liu, Chunmei, Tang, Kaihong, Dong, Xuening, Xue, Longge, Su, Guangming, Zhang, Wenzheng, Jin, Yingyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823654/
https://www.ncbi.nlm.nih.gov/pubmed/31529146
http://dx.doi.org/10.1007/s00011-019-01285-1