Cross Talk between eIF2α and eEF2 Phosphorylation Pathways Optimizes Translational Arrest in Response to Oxidative Stress

The cellular stress response triggers a cascade of events leading to transcriptional reprogramming and a transient inhibition of global protein synthesis, which is thought to be mediated by phosphorylation of eukaryotic initiation factor-2α (eIF2α). Using mouse embryonic fibroblasts (MEFs) and the f...

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Detalles Bibliográficos
Autores principales: Sanchez, Marisa, Lin, Yingying, Yang, Chih-Cheng, McQuary, Philip, Rosa Campos, Alexandre, Aza Blanc, Pedro, Wolf, Dieter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823656/
https://www.ncbi.nlm.nih.gov/pubmed/31627132
http://dx.doi.org/10.1016/j.isci.2019.09.031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823656/
https://www.ncbi.nlm.nih.gov/pubmed/31627132
http://dx.doi.org/10.1016/j.isci.2019.09.031

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