Histone Deacetylase 3 Governs Perinatal Cerebral Development via Neural Stem and Progenitor Cells

We report that cerebrum-specific inactivation of the histone deacetylase 3 (HDAC3) gene causes striking developmental defects in the neocortex, hippocampus, and corpus callosum; post-weaning lethality; and abnormal behaviors, including hyperactivity and anxiety. The defects are due to rapid loss of...

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Detalles Bibliográficos
Autores principales: Li, Lin, Jin, Jianliang, Yang, Xiang-Jiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823663/
https://www.ncbi.nlm.nih.gov/pubmed/31569049
http://dx.doi.org/10.1016/j.isci.2019.09.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823663/
https://www.ncbi.nlm.nih.gov/pubmed/31569049
http://dx.doi.org/10.1016/j.isci.2019.09.015

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