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Crowd Control: Effects of Physical Crowding on Cargo Movement in Healthy and Diseased Neurons
High concentration of cytoskeletal filaments, organelles, and proteins along with the space constraints due to the axon’s narrow geometry lead inevitably to intracellular physical crowding along the axon of a neuron. Local cargo movement is essential for maintaining steady cargo transport in the axo...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823667/ https://www.ncbi.nlm.nih.gov/pubmed/31708745 http://dx.doi.org/10.3389/fncel.2019.00470 |