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Crowd Control: Effects of Physical Crowding on Cargo Movement in Healthy and Diseased Neurons

High concentration of cytoskeletal filaments, organelles, and proteins along with the space constraints due to the axon’s narrow geometry lead inevitably to intracellular physical crowding along the axon of a neuron. Local cargo movement is essential for maintaining steady cargo transport in the axo...

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Detalles Bibliográficos
Autores principales: Sabharwal, Vidur, Koushika, Sandhya P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823667/
https://www.ncbi.nlm.nih.gov/pubmed/31708745
http://dx.doi.org/10.3389/fncel.2019.00470