Sensitive Determination of Proteolytic Proteoforms in Limited Microscale Proteome Samples

Protein N termini unambiguously identify truncated, alternatively translated or modified proteoforms with distinct functions and reveal perturbations in disease. Selective enrichment of N-terminal peptides is necessary to achieve proteome-wide coverage for unbiased identification of site-specific re...

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Detalles Bibliográficos
Autores principales: Weng, Samuel S. H., Demir, Fatih, Ergin, Enes K., Dirnberger, Sabrina, Uzozie, Anuli, Tuscher, Domenic, Nierves, Lorenz, Tsui, Janice, Huesgen, Pitter F., Lange, Philipp F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2019
Materias:
Technological Innovation and Resources
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823850/
https://www.ncbi.nlm.nih.gov/pubmed/31471496
http://dx.doi.org/10.1074/mcp.TIR119.001560

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823850/
https://www.ncbi.nlm.nih.gov/pubmed/31471496
http://dx.doi.org/10.1074/mcp.TIR119.001560

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