NPC1161B, an 8-Aminoquinoline Analog, Is Metabolized in the Mosquito and Inhibits Plasmodium falciparum Oocyst Maturation

Malaria is a major global health threat, with nearly half the world’s population at risk of infection. Given the recently described delayed clearance of parasites by artemisinin-combined therapies, new antimalarials are needed to facilitate the global effort toward elimination and eradication. NPC11...

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Detalles Bibliográficos
Autores principales: Hamerly, Timothy, Tweedell, Rebecca E., Hritzo, Bernadette, Nyasembe, Vincent O., Tekwani, Babu L., Nanayakkara, N. P. Dhammika, Walker, Larry A., Dinglasan, Rhoel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823860/
https://www.ncbi.nlm.nih.gov/pubmed/31708786
http://dx.doi.org/10.3389/fphar.2019.01265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823860/
https://www.ncbi.nlm.nih.gov/pubmed/31708786
http://dx.doi.org/10.3389/fphar.2019.01265

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