Pan-Cancer Analysis of Potential Synthetic Lethal Drug Targets Specific to Alterations in DNA Damage Response

Alterations in DNA damage response (DDR) is one of the several hallmarks of cancer. Genomic instability resulting from a disrupted DDR mechanism is known to contribute to cancer progression, and are subjected to radiation, cytotoxic, or more recently targeted therapies with limited success. Syntheti...

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Detalles Bibliográficos
Autores principales: Das, Shaoli, Camphausen, Kevin, Shankavaram, Uma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823874/
https://www.ncbi.nlm.nih.gov/pubmed/31709193
http://dx.doi.org/10.3389/fonc.2019.01136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823874/
https://www.ncbi.nlm.nih.gov/pubmed/31709193
http://dx.doi.org/10.3389/fonc.2019.01136

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