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Does low-density lipoprotein cholesterol induce inflammation? If so, does it matter? Current insights and future perspectives for novel therapies

BACKGROUND: Dyslipidemia and inflammation are closely interrelated contributors in the pathogenesis of atherosclerosis. Disorders of lipid metabolism initiate an inflammatory and immune-mediated response in atherosclerosis, while low-density lipoprotein cholesterol (LDL-C) lowering has possible plei...

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Detalles Bibliográficos
Autores principales: Jukema, Ruurt A., Ahmed, Tarek A. N., Tardif, Jean-Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824020/
https://www.ncbi.nlm.nih.gov/pubmed/31672136
http://dx.doi.org/10.1186/s12916-019-1433-3