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Does low-density lipoprotein cholesterol induce inflammation? If so, does it matter? Current insights and future perspectives for novel therapies
BACKGROUND: Dyslipidemia and inflammation are closely interrelated contributors in the pathogenesis of atherosclerosis. Disorders of lipid metabolism initiate an inflammatory and immune-mediated response in atherosclerosis, while low-density lipoprotein cholesterol (LDL-C) lowering has possible plei...
Autores principales: | Jukema, Ruurt A., Ahmed, Tarek A. N., Tardif, Jean-Claude |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824020/ https://www.ncbi.nlm.nih.gov/pubmed/31672136 http://dx.doi.org/10.1186/s12916-019-1433-3 |
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