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Endogenous CRISPR-Cas System-Based Genome Editing and Antimicrobials: Review and Prospects
CRISPR-Cas systems adapt “memories” via spacers from viruses and plasmids to develop adaptive immunity against mobile genetic elements. Mature CRISPR RNAs guide CRISPR-associated nucleases to site-specifically cleave target DNA or RNA, providing an efficient genome engineering tool for organisms of...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824031/ https://www.ncbi.nlm.nih.gov/pubmed/31708910 http://dx.doi.org/10.3389/fmicb.2019.02471 |