gem-Difluorobisarylic derivatives: design, synthesis and anti-inflammatory effect

INTRODUCTION: New fluorinated diaryl ethers and bisarylic ketones were designed and evaluated for their anti-inflammatory effects in primary macrophages. METHODS: The synthesis of the designed molecules started from easily accessible and versatile gem-difluoro propargylic derivatives. The desired ar...

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Detalles Bibliográficos
Autores principales: Ayoub, Abeer J., Hariss, Layal, El-Hachem, Nehme, El-Achkar, Ghewa A., Ghayad, Sandra E., Dagher, Oula K., Borghol, Nada, Grée, René, Badran, Bassam, Hachem, Ali, Hamade, Eva, Habib, Aida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824041/
https://www.ncbi.nlm.nih.gov/pubmed/31696161
http://dx.doi.org/10.1186/s13065-019-0640-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824041/
https://www.ncbi.nlm.nih.gov/pubmed/31696161
http://dx.doi.org/10.1186/s13065-019-0640-5

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