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Suppression of nicotinamide phosphoribosyltransferase expression by miR-154 reduces the viability of breast cancer cells and increases their susceptibility to doxorubicin

BACKGROUND: Nicotinamide phosphoribosyltransferase (NAMPT) enzyme acts as the major enzyme in the nicotinamide adenine dinucleotide (NAD) synthesis salvage pathway. Deregulation of NAD could be associated with progression of several cancers such as breast cancer. Here, the consequence of NAMPT inhib...

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Detalles Bibliográficos
Autores principales: Bolandghamat Pour, Zahra, Nourbakhsh, Mitra, Mousavizadeh, Kazem, Madjd, Zahra, Ghorbanhosseini, Seyedeh Sara, Abdolvahabi, Zohreh, Hesari, Zahra, Ezzati Mobasser, Samira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824125/
https://www.ncbi.nlm.nih.gov/pubmed/31675930
http://dx.doi.org/10.1186/s12885-019-6221-0