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Ex vivo tissue slice culture system to measure drug-response rates of hepatic metastatic colorectal cancer

BACKGROUND: The lack of predictive biomarkers or test systems contributes to high failure rates of systemic therapy in metastasized colorectal carcinoma, accounting for a still unfavorable prognosis. Here, we present an ex vivo functional assay to measure drug-response based on a tissue slice cultur...

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Detalles Bibliográficos
Autores principales: Martin, Steve Z., Wagner, Daniel C., Hörner, Nina, Horst, David, Lang, Hauke, Tagscherer, Katrin E., Roth, Wilfried
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824140/
https://www.ncbi.nlm.nih.gov/pubmed/31675944
http://dx.doi.org/10.1186/s12885-019-6270-4