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Histone H3K36I mutation in a metastatic histiocytic tumor of the skull and response to sarcoma chemotherapy
Recurrent somatic missense mutations in histone H3 genes have been identified in subsets of pediatric cancers. H3K36 histone mutations have recently been recognized as oncogenic drivers in rare subsets of malignant soft tissue sarcomas but have not been reported in histiocytic neoplasms. Currently,...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824254/ https://www.ncbi.nlm.nih.gov/pubmed/31645348 http://dx.doi.org/10.1101/mcs.a004606 |