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Histone H3K36I mutation in a metastatic histiocytic tumor of the skull and response to sarcoma chemotherapy

Recurrent somatic missense mutations in histone H3 genes have been identified in subsets of pediatric cancers. H3K36 histone mutations have recently been recognized as oncogenic drivers in rare subsets of malignant soft tissue sarcomas but have not been reported in histiocytic neoplasms. Currently,...

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Detalles Bibliográficos
Autores principales: Snuderl, Matija, Dolgalev, Igor, Heguy, Adriana, Walsh, Michael F., Benayed, Ryma, Jungbluth, Achim A., Ladanyi, Marc, Karajannis, Matthias A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824254/
https://www.ncbi.nlm.nih.gov/pubmed/31645348
http://dx.doi.org/10.1101/mcs.a004606