Dose Determination for a Fixed-Dose Drug Combination: A Phase II Randomized Controlled Trial for Tiotropium/Olodaterol Versus Tiotropium in Patients with COPD

INTRODUCTION: During the clinical development of a fixed-dose combination of drugs, it is best practice to conduct dose-finding studies to determine the optimal dose of each component. The aims of this phase II dose-finding study were to confirm the lung function benefit of adding olodaterol to tiot...

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Detalles Bibliográficos
Autores principales: Maltais, François, Hamilton, Alan, Voß, Florian, Maleki-Yazdi, M. Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2019
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824359/
https://www.ncbi.nlm.nih.gov/pubmed/30843141
http://dx.doi.org/10.1007/s12325-019-00911-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824359/
https://www.ncbi.nlm.nih.gov/pubmed/30843141
http://dx.doi.org/10.1007/s12325-019-00911-y

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