Maximum Tolerated Dose and Pharmacokinetics of Paclitaxel Micellar in Patients with Recurrent Malignant Solid Tumours: A Dose-Escalation Study

INTRODUCTION: A water-soluble Cremophor EL-free formulation of paclitaxel, in which retinoic acid derivates solubilize paclitaxel by forming micelles (paclitaxel micellar), was studied for the first time in man to establish the maximum tolerated dose (MTD) and to characterize the pharmacokinetics (P...

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Detalles Bibliográficos
Autores principales: Borgå, Olof, Henriksson, Roger, Bjermo, Helena, Lilienberg, Elsa, Heldring, Nina, Loman, Niklas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824363/
https://www.ncbi.nlm.nih.gov/pubmed/30879251
http://dx.doi.org/10.1007/s12325-019-00909-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824363/
https://www.ncbi.nlm.nih.gov/pubmed/30879251
http://dx.doi.org/10.1007/s12325-019-00909-6

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